Several clinical studies have shown a positive effect of MeD on the reduction of the risk of developing chronic metabolic diseases such as diabetes mellitus, cardiovascular diseases, arterial hypertension, but also cancer, neurodegenerative diseases and osteoporosis
Conversely, normal oxidative-stress biomarkers do not rule out atherosclerosis, high blood pressure, inherited cardiovascular risk, structural heart disease, or other health concerns
We saw a notable decline in the use of traditional, lower-cost diabetes therapies such as metformin and insulin and a significant rise in the adoption of newer, high-cost therapies such as GLP-1s
Its prevalence is increasing worldwide, and, like obesity, it affects progressively younger populations compared to the past, with potentially greater impact on chronic complications